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Rx only · Tablet · Oral

Estradiol

Estradiol

18 ACTIVE SUPPLIERS — US
openFDA · updated weekly
US67 NDCs
18 active makers
UKComing
soon
CAComing
soon
AUComing
soon
EUComing
soon
RxCUI (US)4083
US makers18 labelers
Packages159
DEA / ScheduleNone

US acquisition costNADAC · per unit

Average across 27 priced NDCs. A benchmark of pharmacy acquisition cost — not a retail quote.

$0.022$0.044$0.066$0.088Dec 2025Apr 2026Jul 2026
$0.070
Latest avg · Jul 22, 2026
-9%
Since Dec 17, 2025
18
Active US suppliers
41%
Top-2 supplier share*

Medicaid dispensing volumeSDUD · per quarter

Prescriptions dispensed under Medicaid (fee-for-service + managed care), summed nationally. The closest free proxy to sales volume — Medicaid only, not all-payer.

93K186K279K372K2025 Q12025 Q22025 Q32025 Q42026 Q1
290K
Rx · 2026 Q1
19.7M
Units dispensed
-6%
Rx vs. year ago
5
Quarters · since 2025 Q1

Who makes it18 active · 0 exited

US labelers as registered with FDA. Repackagers relabel another company's product; share* is of listed packages, not sales.

LabelerTypePackagesStatus
Bryant Ranch Prepackrepackager49SUPPLYING
A-S Medication Solutionsunknown16SUPPLYING
NuCare Pharmaceuticals, Inc.unknown13SUPPLYING
Preferred Pharmaceuticals Inc.unknown12SUPPLYING
Northwind Health Company, LLCunknown9SUPPLYING
Asclemed USA, Inc.unknown9SUPPLYING
REMEDYREPACK INC.repackager7SUPPLYING
PURACAP LABORATORIES, LLCunknown7SUPPLYING
Epic Pharma, LLCunknown7SUPPLYING
NorthStar Rx LLCunknown5SUPPLYING
ANI Pharmaceuticals, Inc.unknown5SUPPLYING
Teva Pharmaceuticals USA, Inc.unknown5SUPPLYING
Direct_Rxunknown4SUPPLYING
PD-Rx Pharmaceuticals, Inc.unknown4SUPPLYING
Proficient Rx LPunknown3SUPPLYING

+ 3 more labelers

Regulatory & supply eventsFDA · US

Shortages, recalls, and registration changes attached to this drug concept.

  • Jan 26, 2022
    RECALLRecall (Class II): ESTRADIOL TABLETS USP, 0.5MG 100 Tablets, Tx Only, Teva Pharmaceuticals USA, Inc., North Wales, PA 19454. NDC: 0555-08…

    CGMP Deviations: Products were exposed to temperatures outside of the products labeled storage conditions. — Recalling firm: CARDINAL HEALTHCARE — Nationwide USA

  • Sep 26, 2019
    RECALLRecall (Class II): Estradiol tablets, 0.5 mg, 100-count bottles, Rx only, Distributed by Epic Pharma, LLC Laurelton, NY 11413, NDC 42806-…

    Presence of Foreign Tablets/Capsules: Estradiol 1 mg was found in a 100 count bottle of Estradiol 0.5 mg Tablets. — Recalling firm: Epic Pharma, LLC — Nationwide within the United States

  • Dec 4, 2018
    RECALLRecall (Class II): Estradiol Tablets, USP, 2 mg, 100-count bottle, Rx Only, Distributed by: Epic Pharma, LLC Laurelton, NY 11413, NDC 4280…

    Presence of foreign tablet/capsule: A single foreign tablet was found in pharmacy dispensed bottle of 30 Estradiol 2 mg tablets. — Recalling firm: Epic Pharma, LLC — U.S.A. Nationwide