PillRx only · Gel · Topical
Estradiol
Brands: Divigel · Estradiol
8 ACTIVE SUPPLIERS — US
openFDA · updated weekly
US35 NDCs
8 active makers
8 active makers
UKComing
soon
soon
CAComing
soon
soon
AUComing
soon
soon
EUComing
soon
soon
US acquisition costNADAC · per unit
Average across 31 priced NDCs. A benchmark of pharmacy acquisition cost — not a retail quote.
$1.867
Latest avg · Jul 22, 2026
-65%
Since Aug 20, 2025
8
Active US suppliers
38%
Top-2 supplier share*
Medicaid dispensing volumeSDUD · per quarter
Prescriptions dispensed under Medicaid (fee-for-service + managed care), summed nationally. The closest free proxy to sales volume — Medicaid only, not all-payer.
7.1K
Rx · 2026 Q1
301K
Units dispensed
+110%
Rx vs. year ago
5
Quarters · since 2025 Q1
Who makes it8 active · 0 exited
US labelers as registered with FDA. Repackagers relabel another company's product; share* is of listed packages, not sales.
| Labeler | Type | Packages | Status |
|---|---|---|---|
| Vertical Pharmaceuticals, LLC | unknown | 10 | SUPPLYING |
| NorthStar Rx LLC | unknown | 5 | SUPPLYING |
| Trigen Laboratories, LLC | unknown | 5 | SUPPLYING |
| Encube Ethicals, Inc. | unknown | 5 | SUPPLYING |
| ANI Pharmaceuticals, Inc. | unknown | 5 | SUPPLYING |
| Padagis Israel Pharmaceuticals Ltd | unknown | 5 | SUPPLYING |
| Bryant Ranch Prepack | repackager | 4 | SUPPLYING |
| Solaris Pharma Corporation | unknown | 1 | SUPPLYING |
Regulatory & supply eventsFDA · US
Shortages, recalls, and registration changes attached to this drug concept.
- May 12, 2026RECALLRecall (Class II): Estradiol Gel, 0.1%, 0.25 mg, 0.25 g per packet, 30 packets per carton, Rx only, Distributed by: ANI Pharmaceuticals, I…
Defective Container; packets were found to be either empty or partially full. — Recalling firm: ANI Pharmaceuticals, Inc. — Nationwide in the USA